Our Research Mission is to build upon and expand existing efforts to develop innovative lines of clinical-translational research into the cause, detection, prevention, and cure of Alzheimer’s Disease and Related Disorders (ADRD) and harmonize CCBH efforts with investigators throughout the University of Miami.
The Comprehensive Center for Brain Health (CCBH) conducts observational and clinical studies related to Lewy Body Dementia, Alzheimer’s Disease, Vascular dementia, Frontotemporal dementia, and other neurodegenerative conditions. CCBH research activities are conducted on site at our Boca Raton, Florida facility or off site as a Co-Leadership multi-site project.
Active Studies in Boca Raton, Florida
Healthy Brain Initiative (HBI)
HBI is an observational study and aims to develop a dementia prevention initiative using a precision medicine approach with personalized tailored interventions in deeply phenotype individuals.
Leuprolide plus Cholinesterase Inhibition to reduce Neurological Decline in Alzheimer’s (LUCINDA)
LUCINDA is a clinical trial to investigate how Leuprolide affects brain structure and/or certain blood tests related to Alzheimer’s Disease.
Dementia with Lewy Body (DLB)
DLB is a Phase 2 clinical trial of CT1812, a disease-modifying compound, that holds potential as a neuroprotective medication for people living with mild to moderate Dementia with Lewy Body.
University of Miami Comprehensive Center for Brain Health is a Lewy Body Dementia Association Research Center of Excellence, which recognizes UM CCBH and Founding Director Dr. James E. Galvin, MD among the nation’s top 20 academic medical institutions providing support to individuals and families living with LBD.
Off-Site Studies
Native Alzheimer’s Disease Resource Centers for Minority Aging Research (NAD-RCMAR)
The study is conducted in Washington and aims to support the career development of early-career scientists and better understand, intervene, and mitigate the Alzheimer’s disease health disparities experienced by American Indians, Alaska Natives, Native Hawaiians, and Pacific Islanders.
Puipui Malu Manatu
(Translation is “Protecting Memories”)
The study is conducted in American Samoa and its goals include determine Alzheimer’s disease and related disorders (ADRD) prevalence, study resilience and vulnerability factors contributing to ADRD in American Samoa and share resources with other investigators. The long-term goals are to foster future research efforts to increase accurate and early diagnosis, expand access to care, and improve health outcomes in American Samoa.
Other Opportunities in CCBH Research
Recruitment Volunteer
A recruitment volunteer spreads awareness about CCBH’s research opportunities and events by connecting with individuals, communities, and groups. This may involve visiting in person, distributing flyers, and building relationships to encourage participation with CCBH. Volunteers are required to complete an application and attend training.
Community Liaison
A community liaison represents their neighborhood, civic group, worship center, or workplace to share information about CCBH’s research opportunities and events. This may include distributing materials, answering questions, and encouraging community participation with CCBH. Liaisons are required to complete an application and attend training.
Community Advisory Board
An advisory board member provides guidance and feedback to help shape CCBH’s research goals, protocols, and long-term plans. This may involve participating in focus groups, interviews, or virtual meetings to share insights, offer suggestions, and support the center’s growth. Potential advisors are required to complete an application and attend orientation.
Donate
Donations, sponsorships, or philanthropic investments expand CCBH’s breadth and depth of efforts in research, clinical care, education and training, and outreach. Your monetory support will contribute to our mission and lead to groundbreaking treatments and better lives for millions of individuals and their families. Join us in making a difference today.