To develop a dementia prevention initiative using a precision medicine approach with personalized tailored interventions in deeply phenotyped individuals

To test and validate a family-centered function focused care (Fam-FFC) plan to improve physical function, cognitive function, and medicoeconomic outcomes in hospitalized patients with dementia. 

To conduct a randomized trial of the Dementia Symptom Management at Home Program for efficacy in improving quality of care for persons living with dementia and their informal caregivers receiving home healthcare.

To develop a national network to study Dementia with Lewy bodies including longitudinal clinical and cognitive characterization, imaging and CSF biomarkers, and autopsy.

To study the effect of disruption of sleep wave sleep duration and efficacy on the accumulation of amyloid protein in the brains of African American older adults.